Single-cell Transcriptome Analysis Indicates New Potential Regulation Mechanism of ACE2 and NPs signaling among heart failure patients infected with SARS-CoV-2

BACKGROUND: COVID-19 patients with comorbidities such as hypertension or heart failure (HF) are associated with poor clinical outcomes. Angiotensin-converting enzyme 2 (ACE2), the critical enzyme for SARS-CoV-2 infection, is broadly expressed in many organs including heart. However, the cellular dis...

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Detalles Bibliográficos
Autores principales: Xu, Dachun, Ma, Mengqiu, Xu, Yanhua, Su, Yang, Ong, Sang-Bing, Hu, Xingdong, Chai, Min, Zhao, Maojun, Li, Hong, Chen, Yingjie, Xu, Xiaojiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7241106/
https://www.ncbi.nlm.nih.gov/pubmed/32511460
http://dx.doi.org/10.1101/2020.04.30.20081257

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