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Repurposing strategies on pyridazinone-based series by pharmacophore- and structure-driven screening

We report here in silico repurposing studies on 52 new pyridazinone-based small-molecules through inverse virtual screening (iVS) methodologies. These analogues were originally designed as formyl peptide receptor (FPR) ligands. As it is sometimes the case in drug discovery programmes, subsequent bio...

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Detalles Bibliográficos
Autores principales:	Floresta, Giuseppe, Crocetti, Letizia, Giovannoni, Maria Paola, Biagini, Pierfrancesco, Cilibrizzi, Agostino
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Taylor & Francis 2020
Materias:	Brief Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7241479/ https://www.ncbi.nlm.nih.gov/pubmed/32367744 http://dx.doi.org/10.1080/14756366.2020.1760261

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