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Evidence for NADPH oxidase activation by GPR40 in pancreatic β-cells
Objective: Investigate the involvement of the fatty acids receptor GPR40 in the assembly and activation of NADPH oxidase and the implications on pancreatic β-cell function. Methods: BRIN-BD11 β-cells were exposed to GPR40 agonist (GW9508) or linoleic acid in different glucose concentrations. Superox...
Autores principales: | Nunes Marsiglio-Librais, Gabriela, Aparecida Vilas-Boas, Eloisa, Carlein, Christopher, Hoffmann, Markus Daniel Alexander, Roma, Leticia Prates, Carpinelli, Angelo Rafael |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7241480/ https://www.ncbi.nlm.nih.gov/pubmed/32354273 http://dx.doi.org/10.1080/13510002.2020.1757877 |
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