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Efficacy and safety of lower dose tenofovir disoproxil fumarate and efavirenz versus standard dose in HIV-infected, antiretroviral-naive adults: a multicentre, randomized, noninferiority trial
Reduced doses of antiretroviral (ARV) drugs may lower toxicity while preserving efficacy. We aimed to evaluate the efficacy of reduced doses of both tenofovir disoproxil fumarate (TDF) and efavirenz for the treatment of HIV-1 infection. In this open-label, non-inferiority trial, HIV-1-infected antir...
Autores principales: | Chen, Jun, Chen, Rong, Shen, Yinzhong, Wei, Hongxia, Wang, Xicheng, Zhang, Renfang, Hu, Zhiliang, Xie, Ronghui, Huang, Qiong, Wang, Jiangrong, Liu, Li, Qi, Tangkai, Wang, Zhenyan, Song, Wei, Tang, Yang, Sun, Jianjun, Lu, Hongzhou |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7241516/ https://www.ncbi.nlm.nih.gov/pubmed/32267205 http://dx.doi.org/10.1080/22221751.2020.1752609 |
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