Efficacy and safety of lower dose tenofovir disoproxil fumarate and efavirenz versus standard dose in HIV-infected, antiretroviral-naive adults: a multicentre, randomized, noninferiority trial

Reduced doses of antiretroviral (ARV) drugs may lower toxicity while preserving efficacy. We aimed to evaluate the efficacy of reduced doses of both tenofovir disoproxil fumarate (TDF) and efavirenz for the treatment of HIV-1 infection. In this open-label, non-inferiority trial, HIV-1-infected antir...

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Detalles Bibliográficos
Autores principales: Chen, Jun, Chen, Rong, Shen, Yinzhong, Wei, Hongxia, Wang, Xicheng, Zhang, Renfang, Hu, Zhiliang, Xie, Ronghui, Huang, Qiong, Wang, Jiangrong, Liu, Li, Qi, Tangkai, Wang, Zhenyan, Song, Wei, Tang, Yang, Sun, Jianjun, Lu, Hongzhou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7241516/
https://www.ncbi.nlm.nih.gov/pubmed/32267205
http://dx.doi.org/10.1080/22221751.2020.1752609

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