Design, synthesis and in vitro antiproliferative activity of new thiazolidinedione-1,3,4-oxadiazole hybrids as thymidylate synthase inhibitors

Thymidylate synthase (TS) has been an attention-grabbing area of research for the treatment of cancers due to their role in DNA biosynthesis. In the present study, we have synthesised a library of thiazolidinedione-1,3,4-oxadiazole hybrids as TS inhibitors. All the synthesised hybrids followed Lipin...

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Detalles Bibliográficos
Autores principales: Alzhrani, Zohor Mohammad Mahdi, Alam, Mohammad Mahboob, Neamatallah, Thikryat, Nazreen, Syed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2020
Materias:
Brief Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7241536/
https://www.ncbi.nlm.nih.gov/pubmed/32354237
http://dx.doi.org/10.1080/14756366.2020.1759581

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7241536/
https://www.ncbi.nlm.nih.gov/pubmed/32354237
http://dx.doi.org/10.1080/14756366.2020.1759581

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