CNS Vasculitis in Anti-Synthetase Syndrome

A 52-year-old woman known to have anti-synthetase syndrome (ASS) with positive anti-alanyl-tRNA synthetase antibody (anti-PL 12) for 4 years presented with headache and progressive deterioration of cognitive functions manifested predominantly by episodes of confusion and dyslexia. Clinical, laborato...

Descripción completa

Detalles Bibliográficos
Autores principales: Shipa, Muhammad, Di Cicco, Maria, Roussou, Euthalia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Mediterranean Journal of Rheumatology (MJR) 2019
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7241664/
https://www.ncbi.nlm.nih.gov/pubmed/32467873
http://dx.doi.org/10.31138/mjr.30.4.220
_version_ 1783537098465214464
author Shipa, Muhammad
Di Cicco, Maria
Roussou, Euthalia
author_facet Shipa, Muhammad
Di Cicco, Maria
Roussou, Euthalia
author_sort Shipa, Muhammad
collection PubMed
description A 52-year-old woman known to have anti-synthetase syndrome (ASS) with positive anti-alanyl-tRNA synthetase antibody (anti-PL 12) for 4 years presented with headache and progressive deterioration of cognitive functions manifested predominantly by episodes of confusion and dyslexia. Clinical, laboratory and radiological evaluation as well as response to treatment was indicative of vasculitis of the central nervous system (CNS). CNS vasculitis is one of the rare manifestations of inflammatory myositis and no case has been reported to suggest CNS vasculitis in ASS.
format Online
Article
Text
id pubmed-7241664
institution National Center for Biotechnology Information
language English
publishDate 2019
publisher The Mediterranean Journal of Rheumatology (MJR)
record_format MEDLINE/PubMed
spelling pubmed-72416642020-05-27 CNS Vasculitis in Anti-Synthetase Syndrome Shipa, Muhammad Di Cicco, Maria Roussou, Euthalia Mediterr J Rheumatol Case Report A 52-year-old woman known to have anti-synthetase syndrome (ASS) with positive anti-alanyl-tRNA synthetase antibody (anti-PL 12) for 4 years presented with headache and progressive deterioration of cognitive functions manifested predominantly by episodes of confusion and dyslexia. Clinical, laboratory and radiological evaluation as well as response to treatment was indicative of vasculitis of the central nervous system (CNS). CNS vasculitis is one of the rare manifestations of inflammatory myositis and no case has been reported to suggest CNS vasculitis in ASS. The Mediterranean Journal of Rheumatology (MJR) 2019-12-31 /pmc/articles/PMC7241664/ /pubmed/32467873 http://dx.doi.org/10.31138/mjr.30.4.220 Text en © 2019 The Mediterranean Journal of Rheumatology (MJR) http://creativecommons.org/licenses/by/4.0/ This work is licensed under and Creative Commons Attribution-NonCommercial 4.0 International License.
spellingShingle Case Report
Shipa, Muhammad
Di Cicco, Maria
Roussou, Euthalia
CNS Vasculitis in Anti-Synthetase Syndrome
title CNS Vasculitis in Anti-Synthetase Syndrome
title_full CNS Vasculitis in Anti-Synthetase Syndrome
title_fullStr CNS Vasculitis in Anti-Synthetase Syndrome
title_full_unstemmed CNS Vasculitis in Anti-Synthetase Syndrome
title_short CNS Vasculitis in Anti-Synthetase Syndrome
title_sort cns vasculitis in anti-synthetase syndrome
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7241664/
https://www.ncbi.nlm.nih.gov/pubmed/32467873
http://dx.doi.org/10.31138/mjr.30.4.220
work_keys_str_mv AT shipamuhammad cnsvasculitisinantisynthetasesyndrome
AT diciccomaria cnsvasculitisinantisynthetasesyndrome
AT roussoueuthalia cnsvasculitisinantisynthetasesyndrome

Ejemplares similares