Aberrant expression of CPSF1 promotes head and neck squamous cell carcinoma via regulating alternative splicing

Alternative mRNA splicing increases protein diversity, and alternative splicing events (ASEs) drive oncogenesis in multiple tumor types. However, the driving alterations that underlie the broad dysregulation of ASEs are incompletely defined. Using head and neck squamous cell carcinoma (HNSCC) as a m...

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Detalles Bibliográficos
Autores principales: Sakai, Akihiro, Ando, Mizuo, Fukusumi, Takahito, Ren, Shuling, Liu, Chao, Qualliotine, Jesse, Haft, Sunny, Sadat, Sayed, Saito, Yuki, Guo, Theresa W., Xu, Guorong, Sasik, Roman, Fisch, Kathleen M., Gutkind, J. Silvio, Fertig, Elana J., Molinolo, Alfredo A., Califano, Joseph A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7241804/
https://www.ncbi.nlm.nih.gov/pubmed/32437477
http://dx.doi.org/10.1371/journal.pone.0233380

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