ALC1/eIF4A1-mediated regulation of CtIP mRNA stability controls DNA end resection

During repair of DNA double-strand breaks, resection of DNA ends influences how these lesions will be repaired. If resection is activated, the break will be channeled through homologous recombination; if not, it will be simply ligated using the non-homologous end-joining machinery. Regulation of res...

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Detalles Bibliográficos
Autores principales: Mejías-Navarro, Fernando, Rodríguez-Real, Guillermo, Ramón, Javier, Camarillo, Rosa, Huertas, Pablo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7241833/
https://www.ncbi.nlm.nih.gov/pubmed/32392243
http://dx.doi.org/10.1371/journal.pgen.1008787

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