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Off-label use of tocilizumab for the treatment of SARS-CoV-2 pneumonia in Milan, Italy
BACKGROUND: Tocilizumab, a humanized monoclonal antibody, targets IL-6 receptors blocking downstream pro-inflammatory effects of IL-6. In preliminary reports it was suggested to be beneficial in patients with severe COVID-19. METHODS: In this open-label prospective study we describe clinical charact...
Autores principales: | Morena, Valentina, Milazzo, Laura, Oreni, Letizia, Bestetti, Giovanna, Fossali, Tommaso, Bassoli, Cinzia, Torre, Alessandro, Cossu, Maria Vittoria, Minari, Caterina, Ballone, Elisabetta, Perotti, Andrea, Mileto, Davide, Niero, Fosca, Merli, Stefania, Foschi, Antonella, Vimercati, Stefania, Rizzardini, Giuliano, Sollima, Salvatore, Bradanini, Lucia, Galimberti, Laura, Colombo, Riccardo, Micheli, Valeria, Negri, Cristina, Ridolfo, Anna Lisa, Meroni, Luca, Galli, Massimo, Antinori, Spinello, Corbellino, Mario |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
European Federation of Internal Medicine. Published by Elsevier B.V.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7241995/ https://www.ncbi.nlm.nih.gov/pubmed/32448770 http://dx.doi.org/10.1016/j.ejim.2020.05.011 |
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