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SARS-CoV-2 and diabetes: New challenges for the disease

A novel small enveloped RNA virus with the typical characteristic of the family to which it belongs, a crown, hence the name coronavirus, appeared in December 2019 in Wuhan, China, and subdued the world to its influence. The particular severity of the disease and higher mortality rates in patients w...

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Autores principales: Cristelo, Cecília, Azevedo, Cláudia, Marques, Joana Moreira, Nunes, Rute, Sarmento, Bruno
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier B.V. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7242186/
https://www.ncbi.nlm.nih.gov/pubmed/32446801
http://dx.doi.org/10.1016/j.diabres.2020.108228
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author Cristelo, Cecília
Azevedo, Cláudia
Marques, Joana Moreira
Nunes, Rute
Sarmento, Bruno
author_facet Cristelo, Cecília
Azevedo, Cláudia
Marques, Joana Moreira
Nunes, Rute
Sarmento, Bruno
author_sort Cristelo, Cecília
collection PubMed
description A novel small enveloped RNA virus with the typical characteristic of the family to which it belongs, a crown, hence the name coronavirus, appeared in December 2019 in Wuhan, China, and subdued the world to its influence. The particular severity of the disease and higher mortality rates in patients with associated morbidities, including hypertension, obesity and diabetes, increases the concern over the consequences of this pandemic. In this review, the features of SARS-CoV-2 will be addressed, as well as the reasons why it poses a particular challenge to diabetic patients. We will also highlight the recent treatment strategies being explored to control this pandemic. Emerging evidence demonstrates that the correct management of diabetes in those patients infected with SARS-CoV-2 is of utmost importance for the viral disease progression, therefore, the importance of blood glucose control will also be addressed.
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spelling pubmed-72421862020-05-22 SARS-CoV-2 and diabetes: New challenges for the disease Cristelo, Cecília Azevedo, Cláudia Marques, Joana Moreira Nunes, Rute Sarmento, Bruno Diabetes Res Clin Pract Article A novel small enveloped RNA virus with the typical characteristic of the family to which it belongs, a crown, hence the name coronavirus, appeared in December 2019 in Wuhan, China, and subdued the world to its influence. The particular severity of the disease and higher mortality rates in patients with associated morbidities, including hypertension, obesity and diabetes, increases the concern over the consequences of this pandemic. In this review, the features of SARS-CoV-2 will be addressed, as well as the reasons why it poses a particular challenge to diabetic patients. We will also highlight the recent treatment strategies being explored to control this pandemic. Emerging evidence demonstrates that the correct management of diabetes in those patients infected with SARS-CoV-2 is of utmost importance for the viral disease progression, therefore, the importance of blood glucose control will also be addressed. Elsevier B.V. 2020-06 2020-05-22 /pmc/articles/PMC7242186/ /pubmed/32446801 http://dx.doi.org/10.1016/j.diabres.2020.108228 Text en © 2020 Elsevier B.V. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Article
Cristelo, Cecília
Azevedo, Cláudia
Marques, Joana Moreira
Nunes, Rute
Sarmento, Bruno
SARS-CoV-2 and diabetes: New challenges for the disease
title SARS-CoV-2 and diabetes: New challenges for the disease
title_full SARS-CoV-2 and diabetes: New challenges for the disease
title_fullStr SARS-CoV-2 and diabetes: New challenges for the disease
title_full_unstemmed SARS-CoV-2 and diabetes: New challenges for the disease
title_short SARS-CoV-2 and diabetes: New challenges for the disease
title_sort sars-cov-2 and diabetes: new challenges for the disease
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7242186/
https://www.ncbi.nlm.nih.gov/pubmed/32446801
http://dx.doi.org/10.1016/j.diabres.2020.108228
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