Understanding Concomitant Physical and Chemical Transformations of Simvastatin During Dry Ball Milling

The present study investigates concomitant processes of solid-state disordering and oxidation of simvastatin during milling. The separate dry ball milling of crystalline and amorphous powders of simvastatin were conducted at ambient temperature for 10 and 60 min each. The relative crystallinity was...

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Detalles Bibliográficos
Autores principales: Modhave, Dattatray, Saraf, Isha, Karn, Anjali, Paudel, Amrit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7242262/
https://www.ncbi.nlm.nih.gov/pubmed/32440782
http://dx.doi.org/10.1208/s12249-020-01687-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7242262/
https://www.ncbi.nlm.nih.gov/pubmed/32440782
http://dx.doi.org/10.1208/s12249-020-01687-z

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