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Manipulating Sirtuin 3 pathway ameliorates renal damage in experimental diabetes

More effective treatments for diabetic nephropathy remain a major unmet clinical need. Increased oxidative stress is one of the most important pathological mechanisms that lead to kidney damage and functional impairment induced by diabetes. Sirtuin 3 (SIRT3) is the main mitochondrial deacetylase and...

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Detalles Bibliográficos
Autores principales:	Locatelli, Monica, Zoja, Carlamaria, Zanchi, Cristina, Corna, Daniela, Villa, Sebastian, Bolognini, Silvia, Novelli, Rubina, Perico, Luca, Remuzzi, Giuseppe, Benigni, Ariela, Cassis, Paola
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7242337/ https://www.ncbi.nlm.nih.gov/pubmed/32439965 http://dx.doi.org/10.1038/s41598-020-65423-0

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