FoxO1–Dio2 signaling axis governs cardiomyocyte thyroid hormone metabolism and hypertrophic growth

Forkhead box O (FoxO) proteins and thyroid hormone (TH) have well established roles in cardiovascular morphogenesis and remodeling. However, specific role(s) of individual FoxO family members in stress-induced growth and remodeling of cardiomyocytes remains unknown. Here, we report that FoxO1, but n...

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Detalles Bibliográficos
Autores principales: Ferdous, Anwarul, Wang, Zhao V., Luo, Yuxuan, Li, Dan L., Luo, Xiang, Schiattarella, Gabriele G., Altamirano, Francisco, May, Herman I., Battiprolu, Pavan K., Nguyen, Annie, Rothermel, Beverly A., Lavandero, Sergio, Gillette, Thomas G., Hill, Joseph A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7242347/
https://www.ncbi.nlm.nih.gov/pubmed/32439985
http://dx.doi.org/10.1038/s41467-020-16345-y

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