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Guanosine fast onset antidepressant-like effects in the olfactory bulbectomy mice model
The treatment of major depressive disorder (MDD) is still a challenge. In the search for novel antidepressants, glutamatergic neuromodulators have been investigated as possible fast-acting antidepressants. Innovative studies suggest that the purine cycle and/or the purinergic signaling can be dysreg...
Autores principales: | de Almeida, Roberto Farina, Pocharski, Camila Barbosa, Rodrigues, Ana Lúcia S., Elisabetsky, Elaine, Souza, Diogo O. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7242421/ https://www.ncbi.nlm.nih.gov/pubmed/32439951 http://dx.doi.org/10.1038/s41598-020-65300-w |
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