Hypoxia-induced GBE1 expression promotes tumor progression through metabolic reprogramming in lung adenocarcinoma

Hypoxia mediates a metabolic switch from oxidative phosphorylation to glycolysis and increases glycogen synthesis. We previously found that glycogen branching enzyme (GBE1) is downstream of the hypoxia-inducible factor-1 (HIF1) signaling pathway in lung adenocarcinoma (LUAD) cells; however, the mole...

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Detalles Bibliográficos
Autores principales: Li, Lifeng, Yang, Li, Fan, Zhirui, Xue, Wenhua, Shen, Zhibo, Yuan, Yongliang, Sun, Xiangdong, Wang, Dan, Lian, Jingyao, Wang, Liping, Zhao, Jie, Zhang, Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7242448/
https://www.ncbi.nlm.nih.gov/pubmed/32439898
http://dx.doi.org/10.1038/s41392-020-0152-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7242448/
https://www.ncbi.nlm.nih.gov/pubmed/32439898
http://dx.doi.org/10.1038/s41392-020-0152-8

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