Objective evaluation for treat to target in Crohn’s disease

BACKGROUND: Crohn’s disease (CD) is a chronic and destructive bowel disease; continued disease activity can lead to penetrating complications. With the recent advent of effective medications, the importance of using a treat-to-target approach to guide therapy is becoming important. METHODS: In this...

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Detalles Bibliográficos
Autores principales: Takenaka, Kento, Kitazume, Yoshio, Fujii, Toshimitsu, Tsuchiya, Kiichiro, Watanabe, Mamoru, Ohtsuka, Kazuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Singapore 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7242491/
https://www.ncbi.nlm.nih.gov/pubmed/32130521
http://dx.doi.org/10.1007/s00535-020-01678-8
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author Takenaka, Kento
Kitazume, Yoshio
Fujii, Toshimitsu
Tsuchiya, Kiichiro
Watanabe, Mamoru
Ohtsuka, Kazuo
author_facet Takenaka, Kento
Kitazume, Yoshio
Fujii, Toshimitsu
Tsuchiya, Kiichiro
Watanabe, Mamoru
Ohtsuka, Kazuo
author_sort Takenaka, Kento
collection PubMed
description BACKGROUND: Crohn’s disease (CD) is a chronic and destructive bowel disease; continued disease activity can lead to penetrating complications. With the recent advent of effective medications, the importance of using a treat-to-target approach to guide therapy is becoming important. METHODS: In this review, we reviewed the previous evidence for evaluating CD lesions. RESULTS: We describe ileocolonoscopy’s role in assessing disease activity, as well as recent progress in modalities, such as balloon-assisted endoscopy, capsule endoscopy, magnetic resonance enterography, computed tomography enterography, and ultrasonography. Advances in modalities have changed CD assessment, with small-bowel involvement becoming more important. CONCLUSIONS: Proper optimization is necessary in clinical practice.
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spelling pubmed-72424912020-06-03 Objective evaluation for treat to target in Crohn’s disease Takenaka, Kento Kitazume, Yoshio Fujii, Toshimitsu Tsuchiya, Kiichiro Watanabe, Mamoru Ohtsuka, Kazuo J Gastroenterol Review BACKGROUND: Crohn’s disease (CD) is a chronic and destructive bowel disease; continued disease activity can lead to penetrating complications. With the recent advent of effective medications, the importance of using a treat-to-target approach to guide therapy is becoming important. METHODS: In this review, we reviewed the previous evidence for evaluating CD lesions. RESULTS: We describe ileocolonoscopy’s role in assessing disease activity, as well as recent progress in modalities, such as balloon-assisted endoscopy, capsule endoscopy, magnetic resonance enterography, computed tomography enterography, and ultrasonography. Advances in modalities have changed CD assessment, with small-bowel involvement becoming more important. CONCLUSIONS: Proper optimization is necessary in clinical practice. Springer Singapore 2020-03-04 2020 /pmc/articles/PMC7242491/ /pubmed/32130521 http://dx.doi.org/10.1007/s00535-020-01678-8 Text en © The Author(s) 2020 Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.
spellingShingle Review
Takenaka, Kento
Kitazume, Yoshio
Fujii, Toshimitsu
Tsuchiya, Kiichiro
Watanabe, Mamoru
Ohtsuka, Kazuo
Objective evaluation for treat to target in Crohn’s disease
title Objective evaluation for treat to target in Crohn’s disease
title_full Objective evaluation for treat to target in Crohn’s disease
title_fullStr Objective evaluation for treat to target in Crohn’s disease
title_full_unstemmed Objective evaluation for treat to target in Crohn’s disease
title_short Objective evaluation for treat to target in Crohn’s disease
title_sort objective evaluation for treat to target in crohn’s disease
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7242491/
https://www.ncbi.nlm.nih.gov/pubmed/32130521
http://dx.doi.org/10.1007/s00535-020-01678-8
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