Linking Phospho-Gonadotropin Regulated Testicular RNA Helicase (GRTH/DDX25) to Histone Ubiquitination and Acetylation Essential for Spermatid Development During Spermiogenesis

GRTH/DDX25 is a testicular RNA helicase expressed in germ cells that plays a crucial role in completion of spermatogenesis. Previously, we demonstrated a missense mutation (R(242)H) of GRTH gene in Japanese infertile patients (5.8%) with non-obstructive azoospermia. This mutation upon expression in...

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Detalles Bibliográficos
Autores principales: Kavarthapu, Raghuveer, Anbazhagan, Rajakumar, Sharma, Ashish K., Shiloach, Joseph, Dufau, Maria L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7242631/
https://www.ncbi.nlm.nih.gov/pubmed/32478068
http://dx.doi.org/10.3389/fcell.2020.00310

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7242631/
https://www.ncbi.nlm.nih.gov/pubmed/32478068
http://dx.doi.org/10.3389/fcell.2020.00310

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