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A JUN N-terminal kinase inhibitor induces ectodomain shedding of the cancer-associated membrane protease Prss14/epithin via protein kinase CβII

Serine protease 14 (Prss14)/epithin is a transmembrane serine protease that plays essential roles in tumor progression and metastasis and therefore is a promising target for managing cancer. Prss14/epithin shedding may underlie its activity in cancer and worsen outcomes; accordingly, a detailed unde...

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Detalles Bibliográficos
Autores principales:	Yoon, Joobyoung, Cho, Youngkyung, Kim, Ki Yeon, Yoon, Min Ji, Lee, Hyo Seon, Jeon, Sangjun Davie, Cho, Yongcheol, Kim, Chungho, Kim, Moon Gyo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2020
Materias:	Cell Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7242708/ https://www.ncbi.nlm.nih.gov/pubmed/32241917 http://dx.doi.org/10.1074/jbc.RA119.011206

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