Hippocampal Synaptic Dysfunction in a Mouse Model of Huntington Disease Is Not Alleviated by Ceftriaxone Treatment

Glutamate transporters, particularly glutamate transporter 1 (GLT-1), help to prevent the adverse effects associated with glutamate toxicity by rapidly clearing glutamate from the extracellular space. Since GLT-1 expression and/or function are reduced in many neurodegenerative diseases, upregulation...

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Detalles Bibliográficos
Autores principales: Wilkie, Crystal M., Barnes, Jocelyn R., Benson, Cherry-Lynn M., Brymer, Kyle J., Nafar, Firoozeh, Parsons, Matthew P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society for Neuroscience 2020
Materias:
Research Article: New Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7242817/
https://www.ncbi.nlm.nih.gov/pubmed/32354757
http://dx.doi.org/10.1523/ENEURO.0440-19.2020

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7242817/
https://www.ncbi.nlm.nih.gov/pubmed/32354757
http://dx.doi.org/10.1523/ENEURO.0440-19.2020

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