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Hippocampal Synaptic Dysfunction in a Mouse Model of Huntington Disease Is Not Alleviated by Ceftriaxone Treatment
Glutamate transporters, particularly glutamate transporter 1 (GLT-1), help to prevent the adverse effects associated with glutamate toxicity by rapidly clearing glutamate from the extracellular space. Since GLT-1 expression and/or function are reduced in many neurodegenerative diseases, upregulation...
Autores principales: | Wilkie, Crystal M., Barnes, Jocelyn R., Benson, Cherry-Lynn M., Brymer, Kyle J., Nafar, Firoozeh, Parsons, Matthew P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Society for Neuroscience
2020
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7242817/ https://www.ncbi.nlm.nih.gov/pubmed/32354757 http://dx.doi.org/10.1523/ENEURO.0440-19.2020 |
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