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From Polygenic Scores to Precision Medicine in Alzheimer’s Disease: A Systematic Review

BACKGROUND: Late-onset Alzheimer’s disease (AD) is highly heritable. The effect of many common genetic variants, single nucleotide polymorphisms (SNPs), confer risk. Variants are clustered in areas of biology, notably immunity and inflammation, cholesterol metabolism, endocytosis, and ubiquitination...

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Detalles Bibliográficos
Autores principales:	Harrison, Judith R., Mistry, Sumit, Muskett, Natalie, Escott-Price, Valentina
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	IOS Press 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7242840/ https://www.ncbi.nlm.nih.gov/pubmed/32250305 http://dx.doi.org/10.3233/JAD-191233

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