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β-Glucan Induces Protective Trained Immunity against Mycobacterium tuberculosis Infection: A Key Role for IL-1

β-glucan is a potent inducer of epigenetic and functional reprogramming of innate immune cells, a process called “trained immunity,” resulting in an enhanced host response against secondary infections. We investigate whether β-glucan exposure confers protection against pulmonary Mycobacterium tuberc...

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Detalles Bibliográficos
Autores principales: Moorlag, Simone J.C.F.M., Khan, Nargis, Novakovic, Boris, Kaufmann, Eva, Jansen, Trees, van Crevel, Reinout, Divangahi, Maziar, Netea, Mihai G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7242907/
https://www.ncbi.nlm.nih.gov/pubmed/32433977
http://dx.doi.org/10.1016/j.celrep.2020.107634