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Prevalence of Hypothyroidism among Dialysis Patients in Palestine: A Cross-Sectional Study
INTRODUCTION: The kidney affects the thyroid gland causing various derangements in its function whenever the kidney is impaired, even with a minor imperfection in its job, and this makes dialysis patients more prone to thyroid disorders with subsequent increase in mortality and morbidity. This study...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7243013/ https://www.ncbi.nlm.nih.gov/pubmed/32455016 http://dx.doi.org/10.1155/2020/2683123 |
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author | Nazzal, Zaher A. Khazneh, Emad N. Rabi, Razan A. Hammoudeh, Ahlam A. Ghanem, Ahmed F. Zaidan, Mohammed A. |
author_facet | Nazzal, Zaher A. Khazneh, Emad N. Rabi, Razan A. Hammoudeh, Ahlam A. Ghanem, Ahmed F. Zaidan, Mohammed A. |
author_sort | Nazzal, Zaher A. |
collection | PubMed |
description | INTRODUCTION: The kidney affects the thyroid gland causing various derangements in its function whenever the kidney is impaired, even with a minor imperfection in its job, and this makes dialysis patients more prone to thyroid disorders with subsequent increase in mortality and morbidity. This study aims to assess the prevalence of thyroid disease (hypo- and hyperthyroidism) among dialysis patients and their associated factors. METHODS: This cross-sectional study was conducted in the dialysis unit of An-Najah National University Hospital. 209 dialysis patients (60% were male, 57.6 ± 14.5 years, mean age) meeting our inclusion criteria were tested for thyrotropin (TSH) and free thyroxine (FT4) in addition to routine laboratory tests. Findings. The prevalence of hypothyroidism was assessed as 16.3% (95% CI = 11.29% to 21.3%), overt hypothyroidism was 9.1%, and subclinical hypothyroidism was 7.2%. Subclinical hyperthyroidism prevalence was 1%, and no overt hyperthyroidism cases were reported. We observed no significant association between thyroid state and age, gender, duration of dialysis, or weight. Discussion. Hypothyroidism (both subclinical and overt type) is commonly seen in dialysis patients, and its symptoms are ordinary complains even in euthyroid dialysis patients, and this warrants screening programs and more studies on the efficacy of thyroid hormone supplements. |
format | Online Article Text |
id | pubmed-7243013 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Hindawi |
record_format | MEDLINE/PubMed |
spelling | pubmed-72430132020-05-22 Prevalence of Hypothyroidism among Dialysis Patients in Palestine: A Cross-Sectional Study Nazzal, Zaher A. Khazneh, Emad N. Rabi, Razan A. Hammoudeh, Ahlam A. Ghanem, Ahmed F. Zaidan, Mohammed A. Int J Nephrol Research Article INTRODUCTION: The kidney affects the thyroid gland causing various derangements in its function whenever the kidney is impaired, even with a minor imperfection in its job, and this makes dialysis patients more prone to thyroid disorders with subsequent increase in mortality and morbidity. This study aims to assess the prevalence of thyroid disease (hypo- and hyperthyroidism) among dialysis patients and their associated factors. METHODS: This cross-sectional study was conducted in the dialysis unit of An-Najah National University Hospital. 209 dialysis patients (60% were male, 57.6 ± 14.5 years, mean age) meeting our inclusion criteria were tested for thyrotropin (TSH) and free thyroxine (FT4) in addition to routine laboratory tests. Findings. The prevalence of hypothyroidism was assessed as 16.3% (95% CI = 11.29% to 21.3%), overt hypothyroidism was 9.1%, and subclinical hypothyroidism was 7.2%. Subclinical hyperthyroidism prevalence was 1%, and no overt hyperthyroidism cases were reported. We observed no significant association between thyroid state and age, gender, duration of dialysis, or weight. Discussion. Hypothyroidism (both subclinical and overt type) is commonly seen in dialysis patients, and its symptoms are ordinary complains even in euthyroid dialysis patients, and this warrants screening programs and more studies on the efficacy of thyroid hormone supplements. Hindawi 2020-05-13 /pmc/articles/PMC7243013/ /pubmed/32455016 http://dx.doi.org/10.1155/2020/2683123 Text en Copyright © 2020 Zaher A. Nazzal et al. http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Research Article Nazzal, Zaher A. Khazneh, Emad N. Rabi, Razan A. Hammoudeh, Ahlam A. Ghanem, Ahmed F. Zaidan, Mohammed A. Prevalence of Hypothyroidism among Dialysis Patients in Palestine: A Cross-Sectional Study |
title | Prevalence of Hypothyroidism among Dialysis Patients in Palestine: A Cross-Sectional Study |
title_full | Prevalence of Hypothyroidism among Dialysis Patients in Palestine: A Cross-Sectional Study |
title_fullStr | Prevalence of Hypothyroidism among Dialysis Patients in Palestine: A Cross-Sectional Study |
title_full_unstemmed | Prevalence of Hypothyroidism among Dialysis Patients in Palestine: A Cross-Sectional Study |
title_short | Prevalence of Hypothyroidism among Dialysis Patients in Palestine: A Cross-Sectional Study |
title_sort | prevalence of hypothyroidism among dialysis patients in palestine: a cross-sectional study |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7243013/ https://www.ncbi.nlm.nih.gov/pubmed/32455016 http://dx.doi.org/10.1155/2020/2683123 |
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