Cargando…

Prevalence of Hypothyroidism among Dialysis Patients in Palestine: A Cross-Sectional Study

INTRODUCTION: The kidney affects the thyroid gland causing various derangements in its function whenever the kidney is impaired, even with a minor imperfection in its job, and this makes dialysis patients more prone to thyroid disorders with subsequent increase in mortality and morbidity. This study...

Descripción completa

Detalles Bibliográficos
Autores principales: Nazzal, Zaher A., Khazneh, Emad N., Rabi, Razan A., Hammoudeh, Ahlam A., Ghanem, Ahmed F., Zaidan, Mohammed A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7243013/
https://www.ncbi.nlm.nih.gov/pubmed/32455016
http://dx.doi.org/10.1155/2020/2683123
_version_ 1783537346274131968
author Nazzal, Zaher A.
Khazneh, Emad N.
Rabi, Razan A.
Hammoudeh, Ahlam A.
Ghanem, Ahmed F.
Zaidan, Mohammed A.
author_facet Nazzal, Zaher A.
Khazneh, Emad N.
Rabi, Razan A.
Hammoudeh, Ahlam A.
Ghanem, Ahmed F.
Zaidan, Mohammed A.
author_sort Nazzal, Zaher A.
collection PubMed
description INTRODUCTION: The kidney affects the thyroid gland causing various derangements in its function whenever the kidney is impaired, even with a minor imperfection in its job, and this makes dialysis patients more prone to thyroid disorders with subsequent increase in mortality and morbidity. This study aims to assess the prevalence of thyroid disease (hypo- and hyperthyroidism) among dialysis patients and their associated factors. METHODS: This cross-sectional study was conducted in the dialysis unit of An-Najah National University Hospital. 209 dialysis patients (60% were male, 57.6 ± 14.5 years, mean age) meeting our inclusion criteria were tested for thyrotropin (TSH) and free thyroxine (FT4) in addition to routine laboratory tests. Findings. The prevalence of hypothyroidism was assessed as 16.3% (95% CI = 11.29% to 21.3%), overt hypothyroidism was 9.1%, and subclinical hypothyroidism was 7.2%. Subclinical hyperthyroidism prevalence was 1%, and no overt hyperthyroidism cases were reported. We observed no significant association between thyroid state and age, gender, duration of dialysis, or weight. Discussion. Hypothyroidism (both subclinical and overt type) is commonly seen in dialysis patients, and its symptoms are ordinary complains even in euthyroid dialysis patients, and this warrants screening programs and more studies on the efficacy of thyroid hormone supplements.
format Online
Article
Text
id pubmed-7243013
institution National Center for Biotechnology Information
language English
publishDate 2020
publisher Hindawi
record_format MEDLINE/PubMed
spelling pubmed-72430132020-05-22 Prevalence of Hypothyroidism among Dialysis Patients in Palestine: A Cross-Sectional Study Nazzal, Zaher A. Khazneh, Emad N. Rabi, Razan A. Hammoudeh, Ahlam A. Ghanem, Ahmed F. Zaidan, Mohammed A. Int J Nephrol Research Article INTRODUCTION: The kidney affects the thyroid gland causing various derangements in its function whenever the kidney is impaired, even with a minor imperfection in its job, and this makes dialysis patients more prone to thyroid disorders with subsequent increase in mortality and morbidity. This study aims to assess the prevalence of thyroid disease (hypo- and hyperthyroidism) among dialysis patients and their associated factors. METHODS: This cross-sectional study was conducted in the dialysis unit of An-Najah National University Hospital. 209 dialysis patients (60% were male, 57.6 ± 14.5 years, mean age) meeting our inclusion criteria were tested for thyrotropin (TSH) and free thyroxine (FT4) in addition to routine laboratory tests. Findings. The prevalence of hypothyroidism was assessed as 16.3% (95% CI = 11.29% to 21.3%), overt hypothyroidism was 9.1%, and subclinical hypothyroidism was 7.2%. Subclinical hyperthyroidism prevalence was 1%, and no overt hyperthyroidism cases were reported. We observed no significant association between thyroid state and age, gender, duration of dialysis, or weight. Discussion. Hypothyroidism (both subclinical and overt type) is commonly seen in dialysis patients, and its symptoms are ordinary complains even in euthyroid dialysis patients, and this warrants screening programs and more studies on the efficacy of thyroid hormone supplements. Hindawi 2020-05-13 /pmc/articles/PMC7243013/ /pubmed/32455016 http://dx.doi.org/10.1155/2020/2683123 Text en Copyright © 2020 Zaher A. Nazzal et al. http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Nazzal, Zaher A.
Khazneh, Emad N.
Rabi, Razan A.
Hammoudeh, Ahlam A.
Ghanem, Ahmed F.
Zaidan, Mohammed A.
Prevalence of Hypothyroidism among Dialysis Patients in Palestine: A Cross-Sectional Study
title Prevalence of Hypothyroidism among Dialysis Patients in Palestine: A Cross-Sectional Study
title_full Prevalence of Hypothyroidism among Dialysis Patients in Palestine: A Cross-Sectional Study
title_fullStr Prevalence of Hypothyroidism among Dialysis Patients in Palestine: A Cross-Sectional Study
title_full_unstemmed Prevalence of Hypothyroidism among Dialysis Patients in Palestine: A Cross-Sectional Study
title_short Prevalence of Hypothyroidism among Dialysis Patients in Palestine: A Cross-Sectional Study
title_sort prevalence of hypothyroidism among dialysis patients in palestine: a cross-sectional study
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7243013/
https://www.ncbi.nlm.nih.gov/pubmed/32455016
http://dx.doi.org/10.1155/2020/2683123
work_keys_str_mv AT nazzalzahera prevalenceofhypothyroidismamongdialysispatientsinpalestineacrosssectionalstudy
AT khaznehemadn prevalenceofhypothyroidismamongdialysispatientsinpalestineacrosssectionalstudy
AT rabirazana prevalenceofhypothyroidismamongdialysispatientsinpalestineacrosssectionalstudy
AT hammoudehahlama prevalenceofhypothyroidismamongdialysispatientsinpalestineacrosssectionalstudy
AT ghanemahmedf prevalenceofhypothyroidismamongdialysispatientsinpalestineacrosssectionalstudy
AT zaidanmohammeda prevalenceofhypothyroidismamongdialysispatientsinpalestineacrosssectionalstudy