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May Polyphenols Have a Role Against Coronavirus Infection? An Overview of in vitro Evidence
The coronavirus infection is constantly diffusing worldwide and the incidence of death is dramatically increasing, representing one of the greatest disasters in human history. Nowadays, no effective therapeutic approaches have been licensed, despite the rising interest of the scientific research in...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7243156/ https://www.ncbi.nlm.nih.gov/pubmed/32574331 http://dx.doi.org/10.3389/fmed.2020.00240 |
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author | Annunziata, Giuseppe Sanduzzi Zamparelli, Marco Santoro, Ciro Ciampaglia, Roberto Stornaiuolo, Mariano Tenore, Gian Carlo Sanduzzi, Alessandro Novellino, Ettore |
author_facet | Annunziata, Giuseppe Sanduzzi Zamparelli, Marco Santoro, Ciro Ciampaglia, Roberto Stornaiuolo, Mariano Tenore, Gian Carlo Sanduzzi, Alessandro Novellino, Ettore |
author_sort | Annunziata, Giuseppe |
collection | PubMed |
description | The coronavirus infection is constantly diffusing worldwide and the incidence of death is dramatically increasing, representing one of the greatest disasters in human history. Nowadays, no effective therapeutic approaches have been licensed, despite the rising interest of the scientific research in this specific field, and the daily growing number of publications, while the need to find novel strategies is urgent. Evidence in the literature reported the antiviral activity of polyphenols, the largest class of bioactive compounds in nature. Interestingly, a limited number of studies investigated the efficacy of polyphenols from different raw materials, directly against coronaviruses. The present manuscript aimed to report this evidence and provide a viewpoint on the possibility to use it as a start point for the development of novel natural approaches against this viral infection, eventually designing further appropriate researches. |
format | Online Article Text |
id | pubmed-7243156 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Frontiers Media S.A. |
record_format | MEDLINE/PubMed |
spelling | pubmed-72431562020-06-03 May Polyphenols Have a Role Against Coronavirus Infection? An Overview of in vitro Evidence Annunziata, Giuseppe Sanduzzi Zamparelli, Marco Santoro, Ciro Ciampaglia, Roberto Stornaiuolo, Mariano Tenore, Gian Carlo Sanduzzi, Alessandro Novellino, Ettore Front Med (Lausanne) Medicine The coronavirus infection is constantly diffusing worldwide and the incidence of death is dramatically increasing, representing one of the greatest disasters in human history. Nowadays, no effective therapeutic approaches have been licensed, despite the rising interest of the scientific research in this specific field, and the daily growing number of publications, while the need to find novel strategies is urgent. Evidence in the literature reported the antiviral activity of polyphenols, the largest class of bioactive compounds in nature. Interestingly, a limited number of studies investigated the efficacy of polyphenols from different raw materials, directly against coronaviruses. The present manuscript aimed to report this evidence and provide a viewpoint on the possibility to use it as a start point for the development of novel natural approaches against this viral infection, eventually designing further appropriate researches. Frontiers Media S.A. 2020-05-15 /pmc/articles/PMC7243156/ /pubmed/32574331 http://dx.doi.org/10.3389/fmed.2020.00240 Text en Copyright © 2020 Annunziata, Sanduzzi Zamparelli, Santoro, Ciampaglia, Stornaiuolo, Tenore, Sanduzzi and Novellino. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
spellingShingle | Medicine Annunziata, Giuseppe Sanduzzi Zamparelli, Marco Santoro, Ciro Ciampaglia, Roberto Stornaiuolo, Mariano Tenore, Gian Carlo Sanduzzi, Alessandro Novellino, Ettore May Polyphenols Have a Role Against Coronavirus Infection? An Overview of in vitro Evidence |
title | May Polyphenols Have a Role Against Coronavirus Infection? An Overview of in vitro Evidence |
title_full | May Polyphenols Have a Role Against Coronavirus Infection? An Overview of in vitro Evidence |
title_fullStr | May Polyphenols Have a Role Against Coronavirus Infection? An Overview of in vitro Evidence |
title_full_unstemmed | May Polyphenols Have a Role Against Coronavirus Infection? An Overview of in vitro Evidence |
title_short | May Polyphenols Have a Role Against Coronavirus Infection? An Overview of in vitro Evidence |
title_sort | may polyphenols have a role against coronavirus infection? an overview of in vitro evidence |
topic | Medicine |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7243156/ https://www.ncbi.nlm.nih.gov/pubmed/32574331 http://dx.doi.org/10.3389/fmed.2020.00240 |
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