Pharmacological inhibition of sodium-proton-exchanger subtype 3-mediated sodium absorption in the gut reduces atrial fibrillation susceptibility in obese spontaneously hypertensive rats

BACKGROUND: Increased sodium uptake has been shown to contribute to hypertension and cardiac end-organ damage. The sodium-proton-exchanger subtype 3 (NHE3) is an important mediator of intestinal sodium absorption. Whether a reduction in intestinal sodium absorption can prevent the development of an...

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Detalles Bibliográficos
Autores principales: Linz, Benedikt, Hohl, Mathias, Mishima, Ricardo, Saljic, Arnela, Lau, Dennis H., Jespersen, Thomas, Schotten, Ulrich, Sanders, Prashanthan, Linz, Dominik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7243186/
https://www.ncbi.nlm.nih.gov/pubmed/32462076
http://dx.doi.org/10.1016/j.ijcha.2020.100534

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