High-density lipoprotein remodelled in hypercholesterolaemic blood induce epigenetically driven down-regulation of endothelial HIF-1α expression in a preclinical animal model

AIMS: High-density lipoproteins (HDLs) are circulating micelles that transport proteins, lipids, and miRNAs. HDL-transported miRNAs (HDL-miRNAs) have lately received attention but their effects on vascular cells are not fully understood. Additionally, whether cardiovascular risk factors affect HDL-m...

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Detalles Bibliográficos
Autores principales: Ben-Aicha, Soumaya, Escate, Rafael, Casaní, Laura, Padró, Teresa, Peña, Esther, Arderiu, Gemma, Mendieta, Guiomar, Badimón, Lina, Vilahur, Gemma
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7243281/
https://www.ncbi.nlm.nih.gov/pubmed/31504272
http://dx.doi.org/10.1093/cvr/cvz239

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