Hyperuricemia Predisposes to the Onset of Diabetes via Promoting Pancreatic β-Cell Death in Uricase-Deficient Male Mice

Clinical studies have shown a link between hyperuricemia (HU) and diabetes, while the exact effect of soluble serum urate on glucose metabolism remains elusive. This study aims to characterize the glucose metabolic phenotypes and investigate the underlying molecular mechanisms using a novel spontane...

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Detalles Bibliográficos
Autores principales: Lu, Jie, He, Yuwei, Cui, Lingling, Xing, Xiaoming, Liu, Zhen, Li, Xinde, Zhang, Hui, Li, Hailong, Sun, Wenyan, Ji, Aichang, Wang, Yao, Yin, Huiyong, Li, Changgui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2020
Materias:
Metabolism
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7243290/
https://www.ncbi.nlm.nih.gov/pubmed/32312870
http://dx.doi.org/10.2337/db19-0704

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