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Pathogenic Role of PPARα Downregulation in Corneal Nerve Degeneration and Impaired Corneal Sensitivity in Diabetes
The purpose of this study was to investigate the protective role of peroxisome proliferator–activated receptor α (PPARα) against diabetic keratopathy and corneal neuropathy. Corneal samples were obtained from human donors with and without diabetes. Streptozotocin-induced diabetic rats and mice were...
Autores principales: | Matlock, H. Greg, Qiu, Fangfang, Malechka, Volha, Zhou, Kelu, Cheng, Rui, Benyajati, Siribhinya, Whelchel, Amy, Karamichos, Dimitrios, Ma, Jian-xing |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Diabetes Association
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7243299/ https://www.ncbi.nlm.nih.gov/pubmed/32213513 http://dx.doi.org/10.2337/db19-0898 |
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