Evaluating anthracycline cardiotoxicity associated single nucleotide polymorphisms in a paediatric cohort with early onset cardiomyopathy

BACKGROUND: Anthracyclines are a mainstay of chemotherapy. However, a relatively frequent adverse outcome of anthracycline treatment is cardiomyopathy. Multiple genetic studies have begun to dissect the complex genetics underlying cardiac sensitivity to the anthracycline drug class. A number of sing...

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Detalles Bibliográficos
Autores principales: McOwan, Timothy N., Craig, Lauren A., Tripdayonis, Anne, Karavendzas, Kathy, Cheung, Michael M., Porrello, Enzo R., Conyers, Rachel, Elliott, David A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7243302/
https://www.ncbi.nlm.nih.gov/pubmed/32477593
http://dx.doi.org/10.1186/s40959-020-00060-0

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