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HPV16 E6/E7 upregulate hTERC mRNA and gene amplification levels by relieving the effect of LKB1 on Sp1 phosphorylation in lung cancer cells

BACKGROUND: There is an immediate need for research on the mechanism underlying telomerase activation and overexpression. MATERIALS & METHODS: A total of 174 patients with lung cancer (n = 106) and benign lung disease (n = 68) were recruited for the current study. The mRNA expression levels of E...

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Detalles Bibliográficos
Autores principales:	Yang, Jing-Hua, Wu, Ming-Zhe, Wang, Xu-Bo, Wang, Shiyu, Qiu, Xue-Shan, Wang, En-Hua, Wu, Guang-Ping
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	SAGE Publications 2020
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7243384/ https://www.ncbi.nlm.nih.gov/pubmed/32499837 http://dx.doi.org/10.1177/1758835920917562

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