Selecting for Altered Substrate Specificity Reveals the Evolutionary Flexibilityof ATP-Binding Cassette Transporters

ATP-binding cassette (ABC) transporters are the largest family of ATP-hydrolyzing transporters, which import or export substrates across membranes, and have members in every sequenced genome. Structural studies and biochemistry highlight the contrast between the global structural similarity of homol...

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Detalles Bibliográficos
Autores principales: Srikant, Sriram, Gaudet, Rachelle, Murray, Andrew W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7243462/
https://www.ncbi.nlm.nih.gov/pubmed/32220325
http://dx.doi.org/10.1016/j.cub.2020.02.077

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