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Elevated Bone Hardness Under Denosumab Treatment, With Persisting Lower Osteocyte Viability During Discontinuation
Denosumab is a potent osteoclast inhibitor targeted to prevent osteoporotic bone loss and thereby reduce fractures in the aging population. Recently, an elevated risk of rebound fractures following denosumab discontinuation was identified, unless patients were transitioned to an alternative antireso...
Autores principales: | Jähn-Rickert, Katharina, Wölfel, Eva M., Jobke, Björn, Riedel, Christoph, Hellmich, Maya, Werner, Mathias, McDonald, Michelle M., Busse, Björn |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7243474/ https://www.ncbi.nlm.nih.gov/pubmed/32499755 http://dx.doi.org/10.3389/fendo.2020.00250 |
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