Neuropeptide Y Enhances Progerin Clearance and Ameliorates the Senescent Phenotype of Human Hutchinson-Gilford Progeria Syndrome Cells

Hutchinson-Gilford progeria syndrome (HGPS, or classical progeria) is a rare genetic disorder, characterized by premature aging, and caused by a de novo point mutation (C608G) within the lamin A/C gene (LMNA), producing an abnormal lamin A protein, termed progerin. Accumulation of progerin causes nu...

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Detalles Bibliográficos
Autores principales: Aveleira, Célia A, Ferreira-Marques, Marisa, Cortes, Luísa, Valero, Jorge, Pereira, Dina, Pereira de Almeida, Luís, Cavadas, Cláudia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
THE JOURNAL OF GERONTOLOGY: Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7243588/
https://www.ncbi.nlm.nih.gov/pubmed/32012215
http://dx.doi.org/10.1093/gerona/glz280

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7243588/
https://www.ncbi.nlm.nih.gov/pubmed/32012215
http://dx.doi.org/10.1093/gerona/glz280

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