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Effects and mechanisms of acupuncture and electroacupuncture for functional dyspepsia: A systematic review

BACKGROUND: Functional dyspepsia (FD) is a common digestive disease with limited therapeutic options. According to evidence-based clinical practice, acupuncture or electroacupuncture (EA) seems to be a promising therapy for patients with FD. However, there is still a lack of systematic reviews that...

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Autores principales: Guo, Yu, Wei, Wei, Chen, Jiande DZ
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Baishideng Publishing Group Inc 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7243644/
https://www.ncbi.nlm.nih.gov/pubmed/32476804
http://dx.doi.org/10.3748/wjg.v26.i19.2440
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author Guo, Yu
Wei, Wei
Chen, Jiande DZ
author_facet Guo, Yu
Wei, Wei
Chen, Jiande DZ
author_sort Guo, Yu
collection PubMed
description BACKGROUND: Functional dyspepsia (FD) is a common digestive disease with limited therapeutic options. According to evidence-based clinical practice, acupuncture or electroacupuncture (EA) seems to be a promising therapy for patients with FD. However, there is still a lack of systematic reviews that have analyzed current clinical trials for a better understanding of mechanisms involved in the ameliorating effect of acupuncture and EA on FD. AIM: To evaluate the results and qualities of existing clinical evidence for researching the underlying mechanisms of acupuncture/EA in treating FD. METHODS: A systematic search of the literature was performed to identify randomized controlled trials in which research on the mechanism of acupuncture or EA was conducted in FD patients. Databases searched included PubMed, EMBASE, Cochrane Library, and Web of Science. Data extraction and quality assessment were completed by two investigators independently and the results of quality evaluation were exported through Review Manager V5.3. RESULTS: Eight studies were included in this review with a total of 17 items for detecting techniques for mechanistic research. Positive effects of acupuncture and EA were observed in regulating gastric motility, gastric accommodation, mental status, gastrointestinal hormones, and central and autonomic functions while improving dyspeptic symptoms and quality of life. CONCLUSION: The key findings of this systematic review support the potential of acupuncture and EA in altering the heterogeneous pathophysiology in patients with FD. However, high-quality studies with well-planned designs are necessary to provide more credible evidence.
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spelling pubmed-72436442020-05-30 Effects and mechanisms of acupuncture and electroacupuncture for functional dyspepsia: A systematic review Guo, Yu Wei, Wei Chen, Jiande DZ World J Gastroenterol Systematic Reviews BACKGROUND: Functional dyspepsia (FD) is a common digestive disease with limited therapeutic options. According to evidence-based clinical practice, acupuncture or electroacupuncture (EA) seems to be a promising therapy for patients with FD. However, there is still a lack of systematic reviews that have analyzed current clinical trials for a better understanding of mechanisms involved in the ameliorating effect of acupuncture and EA on FD. AIM: To evaluate the results and qualities of existing clinical evidence for researching the underlying mechanisms of acupuncture/EA in treating FD. METHODS: A systematic search of the literature was performed to identify randomized controlled trials in which research on the mechanism of acupuncture or EA was conducted in FD patients. Databases searched included PubMed, EMBASE, Cochrane Library, and Web of Science. Data extraction and quality assessment were completed by two investigators independently and the results of quality evaluation were exported through Review Manager V5.3. RESULTS: Eight studies were included in this review with a total of 17 items for detecting techniques for mechanistic research. Positive effects of acupuncture and EA were observed in regulating gastric motility, gastric accommodation, mental status, gastrointestinal hormones, and central and autonomic functions while improving dyspeptic symptoms and quality of life. CONCLUSION: The key findings of this systematic review support the potential of acupuncture and EA in altering the heterogeneous pathophysiology in patients with FD. However, high-quality studies with well-planned designs are necessary to provide more credible evidence. Baishideng Publishing Group Inc 2020-05-21 2020-05-21 /pmc/articles/PMC7243644/ /pubmed/32476804 http://dx.doi.org/10.3748/wjg.v26.i19.2440 Text en ©The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved. http://creativecommons.org/licenses/by-nc/4.0/ This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial.
spellingShingle Systematic Reviews
Guo, Yu
Wei, Wei
Chen, Jiande DZ
Effects and mechanisms of acupuncture and electroacupuncture for functional dyspepsia: A systematic review
title Effects and mechanisms of acupuncture and electroacupuncture for functional dyspepsia: A systematic review
title_full Effects and mechanisms of acupuncture and electroacupuncture for functional dyspepsia: A systematic review
title_fullStr Effects and mechanisms of acupuncture and electroacupuncture for functional dyspepsia: A systematic review
title_full_unstemmed Effects and mechanisms of acupuncture and electroacupuncture for functional dyspepsia: A systematic review
title_short Effects and mechanisms of acupuncture and electroacupuncture for functional dyspepsia: A systematic review
title_sort effects and mechanisms of acupuncture and electroacupuncture for functional dyspepsia: a systematic review
topic Systematic Reviews
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7243644/
https://www.ncbi.nlm.nih.gov/pubmed/32476804
http://dx.doi.org/10.3748/wjg.v26.i19.2440
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