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Neonatal Rhesus Macaques Have Distinct Immune Cell Transcriptional Profiles following HIV Envelope Immunization

HIV-1-infected infants develop broadly neutralizing antibodies (bnAbs) more rapidly than adults, suggesting differences in the neonatal versus adult responses to the HIV-1 envelope (Env). Here, trimeric forms of HIV-1 Env immunogens elicit increased gp120-and gp41-specific antibodies more rapidly in...

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Detalles Bibliográficos
Autores principales:	Han, Qifeng, Bradley, Todd, Williams, Wilton B., Cain, Derek W., Montefiori, David C., Saunders, Kevin O., Parks, Robert J., Edwards, Regina W., Ferrari, Guido, Mueller, Olaf, Shen, Xiaoying, Wiehe, Kevin J., Reed, Steven, Fox, Christopher B., Rountree, Wes, Vandergrift, Nathan A., Wang, Yunfei, Sutherland, Laura L., Santra, Sampa, Moody, M. Anthony, Permar, Sallie R., Tomaras, Georgia D., Lewis, Mark G., Van Rompay, Koen K.A., Haynes, Barton F.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7243677/ https://www.ncbi.nlm.nih.gov/pubmed/32023469 http://dx.doi.org/10.1016/j.celrep.2019.12.091

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