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Chest X-ray features of SARS-CoV-2 in the emergency department: a multicenter experience from northern Italian hospitals

OBJECTIVES: To evaluate the imaging features of routine admission chest X-ray in patients referred for novel Coronavirus 2019 infection. METHODS: All patients referred to the emergency departments, RT-PCR positive for SARS-CoV-2 infection were evaluated. Demographic and clinical data were recorded....

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Autores principales: Ippolito, Davide, Maino, Cesare, Pecorelli, Anna, Allegranza, Pietro, Cangiotti, Cecilia, Capodaglio, Carlo, Mariani, Ilaria, Giandola, Teresa, Gandola, Davide, Bianco, Ilaria, Ragusi, Maria, Franzesi, Cammillo Talei, Corso, Rocco, Sironi, Sandro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7243792/
https://www.ncbi.nlm.nih.gov/pubmed/32469732
http://dx.doi.org/10.1016/j.rmed.2020.106036
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author Ippolito, Davide
Maino, Cesare
Pecorelli, Anna
Allegranza, Pietro
Cangiotti, Cecilia
Capodaglio, Carlo
Mariani, Ilaria
Giandola, Teresa
Gandola, Davide
Bianco, Ilaria
Ragusi, Maria
Franzesi, Cammillo Talei
Corso, Rocco
Sironi, Sandro
author_facet Ippolito, Davide
Maino, Cesare
Pecorelli, Anna
Allegranza, Pietro
Cangiotti, Cecilia
Capodaglio, Carlo
Mariani, Ilaria
Giandola, Teresa
Gandola, Davide
Bianco, Ilaria
Ragusi, Maria
Franzesi, Cammillo Talei
Corso, Rocco
Sironi, Sandro
author_sort Ippolito, Davide
collection PubMed
description OBJECTIVES: To evaluate the imaging features of routine admission chest X-ray in patients referred for novel Coronavirus 2019 infection. METHODS: All patients referred to the emergency departments, RT-PCR positive for SARS-CoV-2 infection were evaluated. Demographic and clinical data were recorded. Two radiologists (8 and 15 years of experience) reviewed all the X-ray images and evaluated the following findings: interstitial opacities, alveolar opacities (AO), AO associated with consolidation, consolidation and/or pleural effusion. We stratified patients in groups according to the time interval between symptoms onset (cut-off 5 days) and X-ray imaging and according to age (cut-off 60 years old). Computed tomography was performed in case of a discrepancy between clinical symptoms, laboratory and X-ray findings, and/or suspicion of complications. RESULTS: A total of 468 patients were tested positive for SARS-CoV-2. Lung lesions primarily manifested as interstitial opacities (71.7%) and AO opacities (60.5%), more frequently bilateral (64.5%) and with a peripheral predominance (62.5%). Patients admitted to the emergency radiology department after 5 days from symptoms onset, more frequently had interstitial and AO opacities, in comparison to those admitted within 5 days, and lung lesions were more frequently bilateral and peripheral. Older patients more frequently presented interstitial and AO opacities in comparison to younger ones. Sixty-eight patients underwent CT that principally showed the presence of ground-glass opacities and consolidations. CONCLUSIONS: The most common X-ray pattern is multifocal and peripheral, associated with interstitial and alveolar opacities. Chest X-ray, compared to CT, can be considered a reliable diagnostic tool, especially in the Emergency setting.
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spelling pubmed-72437922020-05-22 Chest X-ray features of SARS-CoV-2 in the emergency department: a multicenter experience from northern Italian hospitals Ippolito, Davide Maino, Cesare Pecorelli, Anna Allegranza, Pietro Cangiotti, Cecilia Capodaglio, Carlo Mariani, Ilaria Giandola, Teresa Gandola, Davide Bianco, Ilaria Ragusi, Maria Franzesi, Cammillo Talei Corso, Rocco Sironi, Sandro Respir Med Article OBJECTIVES: To evaluate the imaging features of routine admission chest X-ray in patients referred for novel Coronavirus 2019 infection. METHODS: All patients referred to the emergency departments, RT-PCR positive for SARS-CoV-2 infection were evaluated. Demographic and clinical data were recorded. Two radiologists (8 and 15 years of experience) reviewed all the X-ray images and evaluated the following findings: interstitial opacities, alveolar opacities (AO), AO associated with consolidation, consolidation and/or pleural effusion. We stratified patients in groups according to the time interval between symptoms onset (cut-off 5 days) and X-ray imaging and according to age (cut-off 60 years old). Computed tomography was performed in case of a discrepancy between clinical symptoms, laboratory and X-ray findings, and/or suspicion of complications. RESULTS: A total of 468 patients were tested positive for SARS-CoV-2. Lung lesions primarily manifested as interstitial opacities (71.7%) and AO opacities (60.5%), more frequently bilateral (64.5%) and with a peripheral predominance (62.5%). Patients admitted to the emergency radiology department after 5 days from symptoms onset, more frequently had interstitial and AO opacities, in comparison to those admitted within 5 days, and lung lesions were more frequently bilateral and peripheral. Older patients more frequently presented interstitial and AO opacities in comparison to younger ones. Sixty-eight patients underwent CT that principally showed the presence of ground-glass opacities and consolidations. CONCLUSIONS: The most common X-ray pattern is multifocal and peripheral, associated with interstitial and alveolar opacities. Chest X-ray, compared to CT, can be considered a reliable diagnostic tool, especially in the Emergency setting. Elsevier Ltd. 2020 2020-05-22 /pmc/articles/PMC7243792/ /pubmed/32469732 http://dx.doi.org/10.1016/j.rmed.2020.106036 Text en © 2020 Elsevier Ltd. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Article
Ippolito, Davide
Maino, Cesare
Pecorelli, Anna
Allegranza, Pietro
Cangiotti, Cecilia
Capodaglio, Carlo
Mariani, Ilaria
Giandola, Teresa
Gandola, Davide
Bianco, Ilaria
Ragusi, Maria
Franzesi, Cammillo Talei
Corso, Rocco
Sironi, Sandro
Chest X-ray features of SARS-CoV-2 in the emergency department: a multicenter experience from northern Italian hospitals
title Chest X-ray features of SARS-CoV-2 in the emergency department: a multicenter experience from northern Italian hospitals
title_full Chest X-ray features of SARS-CoV-2 in the emergency department: a multicenter experience from northern Italian hospitals
title_fullStr Chest X-ray features of SARS-CoV-2 in the emergency department: a multicenter experience from northern Italian hospitals
title_full_unstemmed Chest X-ray features of SARS-CoV-2 in the emergency department: a multicenter experience from northern Italian hospitals
title_short Chest X-ray features of SARS-CoV-2 in the emergency department: a multicenter experience from northern Italian hospitals
title_sort chest x-ray features of sars-cov-2 in the emergency department: a multicenter experience from northern italian hospitals
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7243792/
https://www.ncbi.nlm.nih.gov/pubmed/32469732
http://dx.doi.org/10.1016/j.rmed.2020.106036
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