Inhibition of Histone Deacetylase (HDAC) Enhances Checkpoint Blockade Efficacy by Rendering Bladder Cancer Cells Visible for T Cell-Mediated Destruction

Inhibitory checkpoint blockade therapy is an immunomodulatory strategy that results in the restoration of T cell functions, and its efficacy depends on the recognition of tumor cells for destruction. Considering the factors at play, one could propose that anti-tumor responses will not occur if tumor...

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Detalles Bibliográficos
Autores principales: Burke, Brianna, Eden, Catherine, Perez, Cynthia, Belshoff, Alex, Hart, Spencer, Plaza-Rojas, Lourdes, Delos Reyes, Michael, Prajapati, Kushal, Voelkel-Johnson, Christina, Henry, Elizabeth, Gupta, Gopal, Guevara-Patiño, José
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7243798/
https://www.ncbi.nlm.nih.gov/pubmed/32500025
http://dx.doi.org/10.3389/fonc.2020.00699

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