Cargando…
Regulation of T Cell Activities in Rheumatoid Arthritis by the Novel Fusion Protein IgD-Fc-Ig
Rheumatoid arthritis (RA) is an autoimmune disease characterized by chronic inflammation and T cell hyper-activation. Emerging evidence has shown that the stimulation of immunoglobulin D (IgD) induces T cell activation and may contribute to disease pathogenesis. In this study, the sIgD concentration...
Autores principales: | Zhang, Jing, Hu, Xiaoxi, Dong, Xiaojie, Chen, Wensheng, Zhang, Lingling, Chang, Yan, Wu, Yujing, Wei, Wei |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7243948/ https://www.ncbi.nlm.nih.gov/pubmed/32499775 http://dx.doi.org/10.3389/fimmu.2020.00755 |
Ejemplares similares
-
Impaired CD27(+)IgD(+) B Cells With Altered Gene Signature in Rheumatoid Arthritis
por: Hu, Fanlei, et al.
Publicado: (2018) -
IgD-Fc-Ig fusion protein, a new biological agent, inhibits T cell function in CIA rats by inhibiting IgD-IgDR-Lck-NF-κB signaling pathways
por: Han, Le, et al.
Publicado: (2020) -
Differential Expression of IgM and IgD Discriminates Two Subpopulations of Human Circulating IgM(+)IgD(+)CD27(+) B Cells That Differ Phenotypically, Functionally, and Genetically
por: Bautista, Diana, et al.
Publicado: (2020) -
Primary Immune Responses and Affinity Maturation Are Controlled by IgD
por: Amendt, Timm, et al.
Publicado: (2021) -
Reduced CD27(−)IgD(−) B Cells in Blood and Raised CD27(−)IgD(−) B Cells in Gut-Associated Lymphoid Tissue in Inflammatory Bowel Disease
por: Pararasa, Chathyan, et al.
Publicado: (2019)