BMAL1 knockdown triggers different colon carcinoma cell fates by altering the delicate equilibrium between AKT/mTOR and P53/P21 pathways

Dysregulation of the circadian timing system (CTS) frequently appears during colorectal cancer (CRC) progression. In order to better understand the role of the circadian clock in CRC progression, this study evaluated in vitro how knockdown of a core circadian protein BMAL1 (BMAL1-KD) influenced the...

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Detalles Bibliográficos
Autores principales: Zhang, Yuan, Devocelle, Aurore, Souza, Lucas, Foudi, Adlen, Tenreira Bento, Sabrina, Desterke, Christophe, Sherrard, Rachel, Ballesta, Annabelle, Adam, Rene, Giron-Michel, Julien, Chang, Yunhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2020
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7244025/
https://www.ncbi.nlm.nih.gov/pubmed/32388500
http://dx.doi.org/10.18632/aging.103124

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