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HOTAIR drives autophagy in midbrain dopaminergic neurons in the substantia nigra compacta in a mouse model of Parkinson’s disease by elevating NPTX2 via miR-221-3p binding

Parkinson’s disease (PD) is a neurodegenerative disorder characterized by progressive cell loss, largely confined to mesencephalic dopamine neurons of the substantia nigra. This study investigated the functional relevance of the HOX transcript antisense intergenic RNA (HOTAIR)/microRNA-221-3 (miR-22...

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Detalles Bibliográficos
Autores principales:	Lang, Yue, Li, Yu, Yu, Haojia, Lin, Lulu, Chen, Xingchi, Wang, Sainan, Zhang, Hui
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals 2020
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7244061/ https://www.ncbi.nlm.nih.gov/pubmed/32396526 http://dx.doi.org/10.18632/aging.103028

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