Cargando…
Insights into Substrate and Inhibitor Selectivity among Human GLUT Transporters through Comparative Modeling and Molecular Docking
[Image: see text] The solute carrier 2 family is composed of 14 transporters, which are members of the major facilitator superfamily. Despite their high physiological importance, there are still many open questions concerning their function and specificity, and in some cases, their physiological sub...
Autores principales: | Ferreira, Rafaela Salgado, Pons, Jean-Luc, Labesse, Gilles |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2019
|
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7244221/ https://www.ncbi.nlm.nih.gov/pubmed/32462103 http://dx.doi.org/10.1021/acsomega.8b03447 |
Ejemplares similares
-
kinDOCK: a tool for comparative docking of protein kinase ligands
por: Martin, Laetitia, et al.
Publicado: (2006) -
Towards accurate high-throughput ligand affinity prediction by exploiting structural ensembles, docking metrics and ligand similarity
por: Schneider, Melanie, et al.
Publicado: (2020) -
@TOME-2: a new pipeline for comparative modeling of protein–ligand complexes
por: Pons, Jean-Luc, et al.
Publicado: (2009) -
Molecular Docking Simulations Provide Insights in the Substrate Binding Sites and Possible Substrates of the ABCC6 Transporter
por: Hosen, Mohammad Jakir, et al.
Publicado: (2014) -
Development of Glucose Transporter (GLUT) Inhibitors
por: Reckzeh, Elena S., et al.
Publicado: (2019)