Retinoic acid synthesis by ALDH1A proteins is dispensable for meiosis initiation in the mouse fetal ovary

In mammals, the timing of meiosis entry is regulated by signals from the gonadal environment. All-trans retinoic acid (ATRA) signaling is considered the key pathway that promotes Stra8 (stimulated by retinoic acid 8) expression and, in turn, meiosis entry. This model, however, is debated because it...

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Detalles Bibliográficos
Autores principales: Chassot, Anne-Amandine, Le Rolle, Morgane, Jolivet, Geneviève, Stevant, Isabelle, Guigonis, Jean-Marie, Da Silva, Fabio, Nef, Serge, Pailhoux, Eric, Schedl, Andreas, Ghyselinck, Norbert B., Chaboissier, Marie-Christine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2020
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7244317/
https://www.ncbi.nlm.nih.gov/pubmed/32494737
http://dx.doi.org/10.1126/sciadv.aaz1261

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