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Leflunomide Inhibits Proliferation and Induces Apoptosis via Suppressing Autophagy and PI3K/Akt Signaling Pathway in Human Bladder Cancer Cells
INTRODUCTION: Bladder cancer is a lethal human malignancy. Currently, treatment for bladder cancer is limited. The anti-tumor effects of leflunomide have attracted much more concern in multiple human cancers. MATERIALS AND METHODS: This study evaluated the anti-tumor effects of leflunomide on cell v...
Autores principales: | Cheng, Li, Wang, Hao, Wang, Zicheng, Huang, Houbao, Zhuo, Dong, Lin, Jian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7244359/ https://www.ncbi.nlm.nih.gov/pubmed/32546957 http://dx.doi.org/10.2147/DDDT.S252626 |
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