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Emergence of 5-HT5A signaling in parvalbumin neurons mediates delayed antidepressant action

The behavioral response to antidepressants is closely associated with physiological changes in the function of neurons in the hippocampal dentate gyrus (DG). Parvalbumin interneurons are a major class of GABAergic neurons, essential for DG function, and are involved in the pathophysiology of several...

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Detalles Bibliográficos
Autores principales: Sagi, Yotam, Medrihan, Lucian, George, Katia, Barney, Miles, McCabe, Kathryn A., Greengard, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7244406/
https://www.ncbi.nlm.nih.gov/pubmed/30804492
http://dx.doi.org/10.1038/s41380-019-0379-3