Survival of COVID-19 patients requires precise immune regulation: The hypothetical immunoprotective role of nicotinic agonists

Summary recent studies have provided novel evidence regarding the effect of nicotine agonists on the prevention or modulation of cytokines storm and reduction of infection. In this study we tried to attempt to address these issues from a therapeutic perspective of nicotine agonists in this manner an...

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Autores principales: Allahverdi Khani, M., SalehiRad, M., Darbeheshti, S., Motaghinejad, M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2020
Materias:
Letter to Editors
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7244420/
https://www.ncbi.nlm.nih.gov/pubmed/32470789
http://dx.doi.org/10.1016/j.mehy.2020.109871
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author Allahverdi Khani, M.
SalehiRad, M.
Darbeheshti, S.
Motaghinejad, M.
author_facet Allahverdi Khani, M.
SalehiRad, M.
Darbeheshti, S.
Motaghinejad, M.
author_sort Allahverdi Khani, M.
collection PubMed
description Summary recent studies have provided novel evidence regarding the effect of nicotine agonists on the prevention or modulation of cytokines storm and reduction of infection. In this study we tried to attempt to address these issues from a therapeutic perspective of nicotine agonists in this manner and we describe one of the most challenging theories of immunotherapy in coronavirus-19 (COVID-19). The analysis of the proposed mechanism goes beyond the physiological consequences of a way to design new strategies to provide anti-inflammatory drugs.
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spelling pubmed-72444202020-05-26 Survival of COVID-19 patients requires precise immune regulation: The hypothetical immunoprotective role of nicotinic agonists Allahverdi Khani, M. SalehiRad, M. Darbeheshti, S. Motaghinejad, M. Med Hypotheses Letter to Editors Summary recent studies have provided novel evidence regarding the effect of nicotine agonists on the prevention or modulation of cytokines storm and reduction of infection. In this study we tried to attempt to address these issues from a therapeutic perspective of nicotine agonists in this manner and we describe one of the most challenging theories of immunotherapy in coronavirus-19 (COVID-19). The analysis of the proposed mechanism goes beyond the physiological consequences of a way to design new strategies to provide anti-inflammatory drugs. Elsevier Ltd. 2020-10 2020-05-23 /pmc/articles/PMC7244420/ /pubmed/32470789 http://dx.doi.org/10.1016/j.mehy.2020.109871 Text en © 2020 Elsevier Ltd. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Letter to Editors
Allahverdi Khani, M.
SalehiRad, M.
Darbeheshti, S.
Motaghinejad, M.
Survival of COVID-19 patients requires precise immune regulation: The hypothetical immunoprotective role of nicotinic agonists
title Survival of COVID-19 patients requires precise immune regulation: The hypothetical immunoprotective role of nicotinic agonists
title_full Survival of COVID-19 patients requires precise immune regulation: The hypothetical immunoprotective role of nicotinic agonists
title_fullStr Survival of COVID-19 patients requires precise immune regulation: The hypothetical immunoprotective role of nicotinic agonists
title_full_unstemmed Survival of COVID-19 patients requires precise immune regulation: The hypothetical immunoprotective role of nicotinic agonists
title_short Survival of COVID-19 patients requires precise immune regulation: The hypothetical immunoprotective role of nicotinic agonists
title_sort survival of covid-19 patients requires precise immune regulation: the hypothetical immunoprotective role of nicotinic agonists
topic Letter to Editors
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7244420/
https://www.ncbi.nlm.nih.gov/pubmed/32470789
http://dx.doi.org/10.1016/j.mehy.2020.109871
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