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Household airborne endotoxin associated with asthma and allergy in elementary school-age children: a case–control study in Kaohsiung, Taiwan
To evaluate the association between the presence of asthma and allergy, and airborne endotoxin in homes of school-age children in Kaohsiung City, Taiwan, with a case–control study design by matching the age and class exposure. Data collection of home visits included an interviewer-administered quest...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7244453/ https://www.ncbi.nlm.nih.gov/pubmed/32212084 http://dx.doi.org/10.1007/s11356-020-07899-x |
Sumario: | To evaluate the association between the presence of asthma and allergy, and airborne endotoxin in homes of school-age children in Kaohsiung City, Taiwan, with a case–control study design by matching the age and class exposure. Data collection of home visits included an interviewer-administered questionnaire and air sampling of participants’ homes for endotoxin, bacteria, and fungi, as well as temperature and relative humidity measurements. Endotoxin was detected in all air samples with a median value of 0.67 EU m(−3). In the adjusted logistic regression model, household airborne endotoxin was associated with higher prevalence of asthma and allergy; OR = 4.88 (95% CI 1.16–20.55) for Q3 (between 0.67 and 1.97 EU m (−3)) vs. Q1 (< 0.31 EU m (−3)), with statistical significance. Airborne fungi were associated with higher prevalence of asthma and allergy; OR = 4.47 (95% CI 1.13–17.69) for Q3 (between 314 and 699 CFU m (−3)) vs. Q1 (< 159 CFU m (−3)) in adjusted logistic regression models. Airborne endotoxin and fungi were significantly associated with children’s asthma and allergy. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (10.1007/s11356-020-07899-x) contains supplementary material, which is available to authorized users. |
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