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BCL-2 family deregulation in colorectal cancer: potential for BH3 mimetics in therapy
Apoptosis is a form of programmed cell death that is essential for tissue homeostasis. De-regulation of the balance between proliferation and apoptosis contributes to tumor initiation. Particularly in the colon where apoptosis is a crucial process in intestinal turnover, inhibition of apoptosis faci...
Autores principales: | Ramesh, Prashanthi, Medema, Jan Paul |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer US
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7244464/ https://www.ncbi.nlm.nih.gov/pubmed/32335811 http://dx.doi.org/10.1007/s10495-020-01601-9 |
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