The acid–base and redox properties of menaquinone MK-4, MK-7, and MK-9 (vitamin K(2)) in DMPC monolayers on mercury

ABSTRACT: The acid–base and redox properties of the menaquinones MK-4, MK-7, and MK-9 (vitamin K(2)) have been studied in DMPC monolayers on mercury electrodes. The monolayers were prepared by adhesion-spreading of menaquinone-spiked DMPC liposomes on a stationary mercury drop electrode. All three m...

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Autores principales: Dharmaraj, Karuppasamy, Román Silva, Javier Ignacio, Kahlert, Heike, Lendeckel, Uwe, Scholz, Fritz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2020
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7244470/
https://www.ncbi.nlm.nih.gov/pubmed/32372117
http://dx.doi.org/10.1007/s00249-020-01433-0
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author Dharmaraj, Karuppasamy
Román Silva, Javier Ignacio
Kahlert, Heike
Lendeckel, Uwe
Scholz, Fritz
author_facet Dharmaraj, Karuppasamy
Román Silva, Javier Ignacio
Kahlert, Heike
Lendeckel, Uwe
Scholz, Fritz
author_sort Dharmaraj, Karuppasamy
collection PubMed
description ABSTRACT: The acid–base and redox properties of the menaquinones MK-4, MK-7, and MK-9 (vitamin K(2)) have been studied in DMPC monolayers on mercury electrodes. The monolayers were prepared by adhesion-spreading of menaquinone-spiked DMPC liposomes on a stationary mercury drop electrode. All three menaquinones possess [Formula: see text] constants outside the experimentally accessible range, i.e., they are higher than about 12. The standard potentials of MK-4, MK-7, and MK-9 in the DMPC monolayers are very similar, i.e., 0.351, 0.326, and 0.330 V (corresponding to the biochemical standard potentials − 0.063, − 0.088, and − 0.085 V). GRAPHIC ABSTRACT: [Image: see text]
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spelling pubmed-72444702020-06-03 The acid–base and redox properties of menaquinone MK-4, MK-7, and MK-9 (vitamin K(2)) in DMPC monolayers on mercury Dharmaraj, Karuppasamy Román Silva, Javier Ignacio Kahlert, Heike Lendeckel, Uwe Scholz, Fritz Eur Biophys J Original Article ABSTRACT: The acid–base and redox properties of the menaquinones MK-4, MK-7, and MK-9 (vitamin K(2)) have been studied in DMPC monolayers on mercury electrodes. The monolayers were prepared by adhesion-spreading of menaquinone-spiked DMPC liposomes on a stationary mercury drop electrode. All three menaquinones possess [Formula: see text] constants outside the experimentally accessible range, i.e., they are higher than about 12. The standard potentials of MK-4, MK-7, and MK-9 in the DMPC monolayers are very similar, i.e., 0.351, 0.326, and 0.330 V (corresponding to the biochemical standard potentials − 0.063, − 0.088, and − 0.085 V). GRAPHIC ABSTRACT: [Image: see text] Springer International Publishing 2020-05-05 2020 /pmc/articles/PMC7244470/ /pubmed/32372117 http://dx.doi.org/10.1007/s00249-020-01433-0 Text en © The Author(s) 2020 Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.
spellingShingle Original Article
Dharmaraj, Karuppasamy
Román Silva, Javier Ignacio
Kahlert, Heike
Lendeckel, Uwe
Scholz, Fritz
The acid–base and redox properties of menaquinone MK-4, MK-7, and MK-9 (vitamin K(2)) in DMPC monolayers on mercury
title The acid–base and redox properties of menaquinone MK-4, MK-7, and MK-9 (vitamin K(2)) in DMPC monolayers on mercury
title_full The acid–base and redox properties of menaquinone MK-4, MK-7, and MK-9 (vitamin K(2)) in DMPC monolayers on mercury
title_fullStr The acid–base and redox properties of menaquinone MK-4, MK-7, and MK-9 (vitamin K(2)) in DMPC monolayers on mercury
title_full_unstemmed The acid–base and redox properties of menaquinone MK-4, MK-7, and MK-9 (vitamin K(2)) in DMPC monolayers on mercury
title_short The acid–base and redox properties of menaquinone MK-4, MK-7, and MK-9 (vitamin K(2)) in DMPC monolayers on mercury
title_sort acid–base and redox properties of menaquinone mk-4, mk-7, and mk-9 (vitamin k(2)) in dmpc monolayers on mercury
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7244470/
https://www.ncbi.nlm.nih.gov/pubmed/32372117
http://dx.doi.org/10.1007/s00249-020-01433-0
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