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Extracellular vesicles from genetically unstable, oncogene-driven cancer cells trigger micronuclei formation in endothelial cells

Oncogenic transformation impacts cancer cell interactions with their stroma, including through formation of abnormal blood vessels. This influence is often attributed to angiogenic growth factors, either soluble, or associated with tumor cell-derived extracellular vesicles (EVs). Here we examine som...

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Detalles Bibliográficos
Autores principales: Chennakrishnaiah, Shilpa, Tsering, Thupten, Gregory, Caroline, Tawil, Nadim, Spinelli, Cristiana, Montermini, Laura, Karatzas, Nicolaos, Aprikian, Saro, Choi, Dongsic, Klewes, Ludger, Mai, Sabine, Rak, Janusz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7244541/
https://www.ncbi.nlm.nih.gov/pubmed/32444772
http://dx.doi.org/10.1038/s41598-020-65640-7