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Extracellular vesicles from genetically unstable, oncogene-driven cancer cells trigger micronuclei formation in endothelial cells
Oncogenic transformation impacts cancer cell interactions with their stroma, including through formation of abnormal blood vessels. This influence is often attributed to angiogenic growth factors, either soluble, or associated with tumor cell-derived extracellular vesicles (EVs). Here we examine som...
Autores principales: | Chennakrishnaiah, Shilpa, Tsering, Thupten, Gregory, Caroline, Tawil, Nadim, Spinelli, Cristiana, Montermini, Laura, Karatzas, Nicolaos, Aprikian, Saro, Choi, Dongsic, Klewes, Ludger, Mai, Sabine, Rak, Janusz |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7244541/ https://www.ncbi.nlm.nih.gov/pubmed/32444772 http://dx.doi.org/10.1038/s41598-020-65640-7 |
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